{"product_id":"a-guide-to-sample-size-for-animal-based-studies-1st-edition","title":"A Guide to Sample Size for Animal-based Studies 1st Edition","description":"\u003ch4\u003e\u003cb\u003eA Guide to Sample Size for Animal-based Studies: Ethical Experimental Design\u003c\/b\u003e\u003c\/h4\u003e\n\u003cp\u003eThis book is an innovative, thorough, and accessible reference work that addresses the critical need to \u003cb\u003e\"rightsize\" animal-based experiments\u003c\/b\u003e. It provides a straightforward, systematic approach to sample size estimation based on the fundamentals of statistical thinking, helping researchers navigate the design trade-offs necessary to simultaneously minimize animal use and produce scientifically rigorous and reliable results.\u003c\/p\u003e\n\u003ch4\u003eKey Features\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cb\u003eEthical Framework (3Rs):\u003c\/b\u003e The book addresses the principles of \u003cb\u003eReplacement, Reduction, and Refinement\u003c\/b\u003e, which comprise the ethical framework for humane animal-based studies, ensuring experiments are both ethical and scientifically valid.\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eStep-by-Step Guidance:\u003c\/b\u003e It offers \u003cb\u003estep-by-step guidance\u003c\/b\u003e in diverse methods for approximating and refining sample size, ensuring a clear and systematic process for experimental design.\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eSpecialized Research Topics:\u003c\/b\u003e It provides detailed treatment of research topics specific to animal-based research, including \u003cb\u003epilot, feasibility, and proof-of-concept studies\u003c\/b\u003e.\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eData and Study Types:\u003c\/b\u003e The book covers sample size approximation methods for different types of data (\u003cb\u003ebinary, continuous, ordinal, time to event\u003c\/b\u003e) and different study types (\u003cb\u003edescription, comparison, nested designs, reference interval construction, and dose-response studies\u003c\/b\u003e).\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003ePractical Examples and Code:\u003c\/b\u003e Includes \u003cb\u003enumerous worked examples\u003c\/b\u003e, using real data from published papers, together with \u003cb\u003eSAS and R code\u003c\/b\u003e, to facilitate application in research.\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eBroad Audience:\u003c\/b\u003e A must-have reference for \u003cb\u003epreclinical and veterinary researchers\u003c\/b\u003e, as well as \u003cb\u003eethical oversight committees and policymakers\u003c\/b\u003e.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Medicalreaders","offers":[{"title":"Default Title","offer_id":42556221587531,"sku":null,"price":44.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0672\/6398\/7787\/files\/61akqArtOsL._SL1360.jpg?v=1780596221","url":"https:\/\/clinicalpaw.com\/products\/a-guide-to-sample-size-for-animal-based-studies-1st-edition","provider":"ClinicalPaw","version":"1.0","type":"link"}